Filtered By:
Vaccination: Vaccines
Countries: China Health
This page shows you your search results in order of date.
Order by Relevance | Date
Total 2452 results found since Jan 2013.
Development in the Inhibition of Dengue Proteases as Drug Targets
CONCLUSION: Different classes of compounds have been reported against DENV, such as nitrogen-containing heterocycles (i.e., imidazole, pyridine, triazoles quinazolines, quinoline, and indole), oxygen-containing heterocycles (i.e., coumarins), and some are mixed heterocyclic compounds of S, N (thiazole, benzothiazine, and thiazolidinediones), and N, O (i.e., oxadiazole). There have been reports of computationally designed compounds to impede the molecular functions of specific structural and non-structural proteins as potential therapeutic targets. This review summarized the current progress in developing dengue protease in...
Source: Current Medicinal Chemistry - September 19, 2023 Category: Chemistry Authors: Muhammad Akram Shehryar Hameed Abbas Hassan Khalid Khan Source Type: research
A large survey on COVID-19 vaccination in patients with Parkinson's disease and healthy population
CONCLUSIONS: The COVID-19 vaccination rate was remarkably lower in PD patients than healthy individuals in China. The approved vaccines have shown an acceptable safety profile. Our findings would offer a reference to guide future clinical decision-making of COVID-19 vaccination and improve the immunization management of PD patients.PMID:37726180 | DOI:10.1016/j.vaccine.2023.09.002
Source: Vaccine - September 19, 2023 Category: Allergy & Immunology Authors: Chao Han Zhen Zhen Zhao Piu Chan Fang Li Chun Ling Chi Xin Zhang Yan Zhao Jing Chen Jing Hong Ma Source Type: research
Development in the Inhibition of Dengue Proteases as Drug Targets
CONCLUSION: Different classes of compounds have been reported against DENV, such as nitrogen-containing heterocycles (i.e., imidazole, pyridine, triazoles quinazolines, quinoline, and indole), oxygen-containing heterocycles (i.e., coumarins), and some are mixed heterocyclic compounds of S, N (thiazole, benzothiazine, and thiazolidinediones), and N, O (i.e., oxadiazole). There have been reports of computationally designed compounds to impede the molecular functions of specific structural and non-structural proteins as potential therapeutic targets. This review summarized the current progress in developing dengue protease in...
Source: Current Medicinal Chemistry - September 19, 2023 Category: Chemistry Authors: Muhammad Akram Shehryar Hameed Abbas Hassan Khalid Khan Source Type: research
Regulatory perspective for quality evaluation of lipid nanoparticle-based mRNA vaccines in China
Biologicals. 2023 Sep 12;84:101700. doi: 10.1016/j.biologicals.2023.101700. Online ahead of print.ABSTRACTIn recent years, urgent unmet medical needs due to the COVID-19 pandemic have accelerated the application of mRNA technology in vaccine development, leading to some of the first approvals of mRNA vaccines in human history by regulatory agencies around the world. For market authorization, comprehensive chemistry, manufacturing and control (CMC) information is required to assure the safety and quality consistency of mRNA vaccines. Evaluating mRNA vaccines for new virus variants poses a challenge for regulators, given the...
Source: Biologicals : Journal of the International Association of Biological Standardization - September 14, 2023 Category: Biotechnology Authors: Jiaqi Lu Wei Wei Wu He Source Type: research
COVID-19 transmission driven by age-group mathematical model in Shijiazhuang City of China
CONCLUSIONS: Shijiazhuang epidemic was the first COVID-19 outbreak in the rural areas in Hebei Province of Northern China. The targeted interventions adopted in early 2021 were effective to halt the transmission due to the implementation of a strict and village-wide closure. However we found that age group profile and NPIs played critical rules to successfully contain Shijiazhuang epidemic, which should be considered by public health policies in rural areas of mainland China during the dynamic zero-COVID policy.PMID:37706095 | PMC:PMC10495604 | DOI:10.1016/j.idm.2023.08.004
Source: Rural Remote Health - September 14, 2023 Category: Rural Health Authors: Fengying Wei Ruiyang Zhou Zhen Jin Senzhong Huang Zhihang Peng Jinjie Wang Ximing Xu Xinyan Zhang Jun Xu Yao Bai Xiaoli Wang Bulai Lu Zhaojun Wang Jianguo Xu Source Type: research
Regulatory perspective for quality evaluation of lipid nanoparticle-based mRNA vaccines in China
Biologicals. 2023 Sep 12;84:101700. doi: 10.1016/j.biologicals.2023.101700. Online ahead of print.ABSTRACTIn recent years, urgent unmet medical needs due to the COVID-19 pandemic have accelerated the application of mRNA technology in vaccine development, leading to some of the first approvals of mRNA vaccines in human history by regulatory agencies around the world. For market authorization, comprehensive chemistry, manufacturing and control (CMC) information is required to assure the safety and quality consistency of mRNA vaccines. Evaluating mRNA vaccines for new virus variants poses a challenge for regulators, given the...
Source: Biologicals : Journal of the International Association of Biological Standardization - September 14, 2023 Category: Biotechnology Authors: Jiaqi Lu Wei Wei Wu He Source Type: research
COVID-19 transmission driven by age-group mathematical model in Shijiazhuang City of China
CONCLUSIONS: Shijiazhuang epidemic was the first COVID-19 outbreak in the rural areas in Hebei Province of Northern China. The targeted interventions adopted in early 2021 were effective to halt the transmission due to the implementation of a strict and village-wide closure. However we found that age group profile and NPIs played critical rules to successfully contain Shijiazhuang epidemic, which should be considered by public health policies in rural areas of mainland China during the dynamic zero-COVID policy.PMID:37706095 | PMC:PMC10495604 | DOI:10.1016/j.idm.2023.08.004
Source: Rural Remote Health - September 14, 2023 Category: Rural Health Authors: Fengying Wei Ruiyang Zhou Zhen Jin Senzhong Huang Zhihang Peng Jinjie Wang Ximing Xu Xinyan Zhang Jun Xu Yao Bai Xiaoli Wang Bulai Lu Zhaojun Wang Jianguo Xu Source Type: research
Regulatory perspective for quality evaluation of lipid nanoparticle-based mRNA vaccines in China
Biologicals. 2023 Sep 12;84:101700. doi: 10.1016/j.biologicals.2023.101700. Online ahead of print.ABSTRACTIn recent years, urgent unmet medical needs due to the COVID-19 pandemic have accelerated the application of mRNA technology in vaccine development, leading to some of the first approvals of mRNA vaccines in human history by regulatory agencies around the world. For market authorization, comprehensive chemistry, manufacturing and control (CMC) information is required to assure the safety and quality consistency of mRNA vaccines. Evaluating mRNA vaccines for new virus variants poses a challenge for regulators, given the...
Source: Biologicals : Journal of the International Association of Biological Standardization - September 14, 2023 Category: Biotechnology Authors: Jiaqi Lu Wei Wei Wu He Source Type: research
Vaccination coverage survey of children aged 1-3 years in Beijing, China, 2005-2021
CONCLUSION: The coverage level and service quality of routine immunization in Beijing were relatively high. However, as influenced by COVID-19 epidemics, both on-time and in-time vaccination rates decreased significantly, except for BCG and HepB. Under the background of COVID-19 pandemic, the keys to maintain high level of vaccination coverage include flexible immunization service time to ensure the guardians bringing their children for vaccination timely, and more attention from providers to the doses after children's first birthday.PMID:37709591 | DOI:10.1016/j.vaccine.2023.08.015
Source: Vaccine - September 14, 2023 Category: Allergy & Immunology Authors: Wen-Yan Ji Dong-Lei Liu Rui Yu Liang Miao Qian-Li Yuan Luo-Dan Suo Jian-Ping Yu Source Type: research
